Posts tagged anti-tuberculotics

Rifampicin-Isoniazid-Tablets-Ifazex-2

Rifampicin

Generic Name: rifampicin/rifampin

Brand Name: Rifadin, Rimactane

General Action: Antibiotic, Antituberculotic (first line)

Stock Dose: Capsules-150,300mg; powder-600mg

Specific Action:

Inhibits DNA-dependent RNA polymerase activity in susceptible bacterial cells.

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Streptomycin

Generic Name: streptomycin sulfate

General Action: Antibiotic, anti-tubercular,anti-infective

Specific Action

Inhibits CHON synthesis strains of gram negative bacteria, mechanisms of lethal action and fully understood, but functional integrity of cell membrane appears to be disrupted.

Indication

Infections caused by susceptible strain of mycobacterium tuberculosis.

Serious infections caused by susceptible strains of Yersinia Pestis

Contraindication

Allergy to aminoglycosides, More >

Isoniazid

Generic name: Isoniazid

Brand name: Niazid

General Action: Antituberculic

This medication is used with other medications to treat active tuberculosis (TB) infections or alone to prevent those who have a positive TB test from developing symptoms of TB. Isoniazid belongs to a class of drugs known as antibiotics that are active against tuberculosis. Interferes with lipid More >
Ethambutol

Ethambutol

Generic name: Ethambutol

Brand name: Myambutol, Servambutol

Classification: Antituberculotic

Action

Ethambutol is bacteriostatic against actively growing TB bacilli, it works by obstructing the formation of cell wall. Mycolic acids attach to the 5′-hydroxyl groups of D-arabinose residues of arabinogalactan and form mycolyl-arabinogalactan-peptidoglycan complex in the cell wall. It disrupts arabinogalactan synthesis by inhibiting the enzyme arabinosyl transferase. More >