Safety and Infection Control NCLEX Practice Quiz (75 Questions)

Safety and Infection Control NCLEX Practice Quiz (75 Questions)

Welcome to your NCLEX practice quiz on Safety and Infection Control. According to the NCLEX-RN test plan, about 9 to 15% of questions will come from this subcategory that includes content about the “nurse’s ability required to protect clients, families, and healthcare personnel from health and environmental hazards.” Good luck, and hope you will learn a lot from this quiz.

Safety and Infection Control Nursing Test Banks

For this nursing test bank, we have included 75 NCLEX practice questions related to the Safety and Infection Control subcategory divided into three sets. Patient safety and infection control are essential and vital components of quality nursing care. A nurse’s ability to think critically and use this knowledge in the delivery of nursing care is essential to the well-being of the patients.

Quiz Guidelines

How These Quizzes Work

A quick guide before you start. It takes less than a minute to read.

Practice Exams

Untimed

Learn at your own pace in a low-pressure setting.

  • Instant feedback with explanations
  • Spot weak areas and review core concepts
  • Build confidence before a real exam

Best for: learning or reviewing a topic

Challenge Exams

2 min / item

Test your readiness under simulated exam conditions.

  • Timed, like the real exam
  • Tougher question sets
  • Benchmark your score before exam day

Best for: final review and self-assessment

How to take a quiz

  1. Start:Click Start Quiz to begin.
  2. Answer every item:Your score and rationales appear only after the last question.
  3. Review:Click View Questions to read the rationale for each answer.

100% free, always. No sign-ups, no registration, and we will never ask for your credit card or personal information to use our practice questions.

Got a score to share or a question about an item? Leave it in the comments, we read every one.

Quizzes included in this guide are:

Recommended books and resources for your NCLEX success:

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Saunders Comprehensive Review for the NCLEX-RN Examination
The go-to NCLEX-RN content review by Linda Anne Silvestri, with more than 5,700 practice questions across the book and online, test-taking strategies, and Next Generation NCLEX items. A new edition is due in late 2026.

Saunders Comprehensive Review for the NCLEX-RN Examination

Strategies for Student Success on the Next Generation NCLEX (NGN) Test Items
The 2025 edition of Silvestri’s guide to the Next Generation NCLEX. It walks through each NGN item type with strategies for applying clinical judgment to case studies and stand-alone items.

Strategies for Student Success on the Next Generation NCLEX (NGN) Test Items

Kaplan NCLEX-RN Prep, Twenty-sixth Edition (2026)
Kaplan’s 2026 edition includes a full-length practice test and Kaplan’s proven strategies for breaking down NCLEX-style questions, including the Next Generation format.

Kaplan NCLEX-RN Prep, Twenty-sixth Edition (2026)

Illustrated Study Guide for the NCLEX-RN Exam
The 2025 edition of Zerwekh’s visual review uses cartoons, mnemonics, and memory notecards to make key nursing concepts easier to understand and remember.

Illustrated Study Guide for the NCLEX-RN Exam

Lippincott Q&A Review for NCLEX-RN
A question-and-answer review organized by clinical area, with rationales for both correct and incorrect answers to help you learn from every question.

Lippincott Q&A Review for NCLEX-RN

Saunders Comprehensive Review for the NCLEX-PN Examination
Silvestri’s 2024 content review and practice questions written specifically for the NCLEX-PN exam, with test-taking strategies for practical nursing students.

Saunders Comprehensive Review for the NCLEX-PN Examination

An investment in knowledge pays the best interest. Keep up the pace and continue learning with these practice quizzes:

About the Author

Paul Martin R.N. brings his wealth of experience from five years as a medical-surgical nurse to his role as a nursing instructor and writer for Nurseslabs, where he shares his expertise in nursing management, emergency care, critical care, infection control, and public health to help students and nurses become the best version of themselves and elevate the nursing profession.

More articles by this author →

12 responses to “Safety and Infection Control NCLEX Practice Quiz (75 Questions)”

  1. Cel Avatar
    Cel

    In # 5 the correct answer should be letter B right?

  2. Tamaria Johnson Avatar
    Tamaria Johnson

    Please review question #5 in Safety and Infection Control NCLEX Practice Exam (Set 2: 25 Questions) I chose the correct answer which was cool air dryer and it was marked wrong. But in the rationales it had it correct. Thank you

    1. Matt Vera, BSN, R.N. Avatar
      Matt Vera, BSN, R.N.

      Corrected! Thank you for letting us know.

  3. Gary Downs Avatar
    Gary Downs

    in the first set of questions #16 about doing CPR. your rational for the answer being what it is states “The nurse should use the heel of one hand at the center of the chest, then place the heel of the other hand on top of the first hand and lace fingers together and give 30 compressions that are about 1” to 1½” deep.”

    this is actually incorrect. per the American Heart Association, depth of compression on children is about 2 inches. answer C is more correct than D. just think the answers should be worded better and rationale should be corrected in the depth.

  4. Guest Avatar
    Guest

    Question 19 regarding the child in foster care. Foster Parents do not have permission to sign informed consent on invasive procedures and need Social Worker permission. Most often the hospital/clinic will request a signature from Social Worker. The child is in the CUSTODY of the state and the CARE of the foster parent.

  5. Kumari Avatar
    Kumari

    Thank you very much. It is a great site, very helpful.
    Please kindly review the answers of the following:
    Safety and Infection Control NCLEX Practice Exam | Quiz #2: Question 25
    The posted answers were not correspond to the Question #25. Thanks again.

    1. Matt Vera BSN, R.N. Avatar
      Matt Vera BSN, R.N.

      Thanks Kumari, this has been fixed! :)

  6. miss_eileen Avatar
    miss_eileen

    Hello!

    For Q#25 for Safety and Infection Control NCLEX Practice Exam Quiz #2, the rationale given does not match the question & its answer choices. Can you fix this, please?

    1. Matt Vera BSN, R.N. Avatar
      Matt Vera BSN, R.N.

      Fixed. Thanks for letting us know! :)

  7. piyanee isaraphanich Avatar
    piyanee isaraphanich

    the test was completed how i can get the certificate or anything elses to be done

    1. Matt Vera BSN, R.N. Avatar
      Matt Vera BSN, R.N.

      Hello Piyanee, Thanks for completing the test! Just to let you know, currently, we don’t offer certificates for the quizzes on our platform. They’re mainly designed for self-assessment and practice. However, you’re welcome to try out other quizzes we have available to further strengthen your knowledge. It’s a great way to keep testing your skills and learning! If you have any other questions or need guidance on specific topics, feel free to reach out.

  8. Jabir Sunemo Avatar
    Jabir Sunemo

    Good, but how open are the questions listed in the above

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