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Cancer & Oncology Nursing NCLEX Practice Quiz (170 Questions)

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By Paul Martin, BSN, R.N.

In this nursing test bank, review cancer and oncology nursing concepts with these NCLEX practice questions. Test your competence in the assessment, diagnosis, and nursing management of patients with cancer. This quiz aims to help student nurses grasp and master the concepts of oncology nursing.

Cancer & Oncology Nursing Test Banks

Included topics in this NCLEX practice questions (with rationales) for cancer and oncology nursing are oncology nursing, Hodgkin’s disease, lung cancer, nursing care of patients undergoing chemotherapy, brachytherapy, laryngeal cancer, colon cancer, and more! This nursing test bank includes 170 practice questions.

Quiz Guidelines

Before you start, here are some examination guidelines and reminders you must read:

  1. Practice Exams: Engage with our Practice Exams to hone your skills in a supportive, low-pressure environment. These exams provide immediate feedback and explanations, helping you grasp core concepts, identify improvement areas, and build confidence in your knowledge and abilities.
  2. Challenge Exams: Take our Challenge Exams to test your mastery and readiness under simulated exam conditions. These exams offer a rigorous question set to assess your understanding, prepare you for actual examinations, and benchmark your performance.
    • You’re given 2 minutes per item.
    • For Challenge Exams, click on the “Start Quiz” button to start the quiz.
  3. Complete the quiz: Ensure that you answer the entire quiz. Only after you’ve answered every item will the score and rationales be shown.
  4. Learn from the rationales: After each quiz, click on the “View Questions” button to understand the explanation for each answer.
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  6. Share your thoughts: We’d love your feedback, scores, and questions! Please share them in the comments below.

Quizzes included in this guide are:

Recommended books and resources for your NCLEX success:

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Saunders Comprehensive Review for the NCLEX-RN
Saunders Comprehensive Review for the NCLEX-RN Examination is often referred to as the best nursing exam review book ever. More than 5,700 practice questions are available in the text. Detailed test-taking strategies are provided for each question, with hints for analyzing and uncovering the correct answer option.

Strategies for Student Success on the Next Generation NCLEX® (NGN) Test Items
Next Generation NCLEX®-style practice questions of all types are illustrated through stand-alone case studies and unfolding case studies. NCSBN Clinical Judgment Measurement Model (NCJMM) is included throughout with case scenarios that integrate the six clinical judgment cognitive skills.

Saunders Q & A Review for the NCLEX-RN® Examination
This edition contains over 6,000 practice questions with each question containing a test-taking strategy and justifications for correct and incorrect answers to enhance review. Questions are organized according to the most recent NCLEX-RN test blueprint Client Needs and Integrated Processes. Questions are written at higher cognitive levels (applying, analyzing, synthesizing, evaluating, and creating) than those on the test itself.

NCLEX-RN Prep Plus by Kaplan
The NCLEX-RN Prep Plus from Kaplan employs expert critical thinking techniques and targeted sample questions. This edition identifies seven types of NGN questions and explains in detail how to approach and answer each type. In addition, it provides 10 critical thinking pathways for analyzing exam questions.

Illustrated Study Guide for the NCLEX-RN® Exam
The 10th edition of the Illustrated Study Guide for the NCLEX-RN Exam, 10th Edition. This study guide gives you a robust, visual, less-intimidating way to remember key facts. 2,500 review questions are now included on the Evolve companion website. 25 additional illustrations and mnemonics make the book more appealing than ever.

NCLEX RN Examination Prep Flashcards (2023 Edition)
NCLEX RN Exam Review FlashCards Study Guide with Practice Test Questions [Full-Color Cards] from Test Prep Books. These flashcards are ready for use, allowing you to begin studying immediately. Each flash card is color-coded for easy subject identification.

An investment in knowledge pays the best interest. Keep up the pace and continue learning with these practice quizzes:

  • Nursing Test Bank: Free Practice Questions UPDATED!
    Our most comprehenisve and updated nursing test bank that includes over 3,500 practice questions covering a wide range of nursing topics that are absolutely free!
  • NCLEX Questions Nursing Test Bank and Review UPDATED!
    Over 1,000+ comprehensive NCLEX practice questions covering different nursing topics. We’ve made a significant effort to provide you with the most challenging questions along with insightful rationales for each question to reinforce learning.
Paul Martin R.N. brings his wealth of experience from five years as a medical-surgical nurse to his role as a nursing instructor and writer for Nurseslabs, where he shares his expertise in nursing management, emergency care, critical care, infection control, and public health to help students and nurses become the best version of themselves and elevate the nursing profession.

10 thoughts on “Cancer & Oncology Nursing NCLEX Practice Quiz (170 Questions)”

  1. Question 6 states “Which statement by the patient warrants further teaching by the nurse” and all of the options appear to be statements from the nurse – to the patient. Very confusing. Question 5 also states the wrong answer is “Faster growing cells are more susceptible to chemo” and further explains the correct answer is “Faster growing cells are more susceptible to chemo”.

    • Hello Kandis!

      The necessary corrections have been made. Thank you for bringing that to our attention.

  2. Dear Paul, thanks a lot for providing these quizzes which are helping me a lot.

    In question 5, I keep thinking the answer is A i.e. Faster growing cells are more susceptible to chemotherapy. You indicate though that the option is B i.e. Faster growing cells are less susceptible to chemotherapy but the explanation given for option B seems to support option A. Please help clarify.

    Thank you

  3. Hi Paul. As a nationally certified oncology nurse with over 35 years of experience, I thought some of the questions were strange or at least lacking context. In Q1, the question says during hospitalization – but the potential answers include side effects that occur months to years after treatment is complete. In Q11, breast self-exam is not included in any national screening guidelines and is rarely encouraged even for persons at high-risk. In Q14, pleural effusion is a late sign, not a warning sign. In Q22 you have assumed all terminal lung cancer pts have pain but emotional care and dyspnea palliation are more prevalent. In Q29, a CBC prior to administering chemotherapy is a national standard of care. In Q37 all of those require further instructions. Maybe adding some details or more context would be helpful.

  4. Q35 Says: Surgical procedure to treat breast cancer involves the removal of the entire breast, pectoralis major muscle and the axillary lymph nodes is a modified radical mastectomy. This is incorrect because a MODIFIED mastectomy preserves the pectoralis major muscle. Wouldn’t the correct answer be a radical mastectomy?


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