An antidote is a substance that can counteract a form of poisoning. The term antidote is a Greek word meaning “given against”.

This post will help you familiarize with the common antidotes that are used in the hospital setting.

The following are antidotes that should be familiarized by the nurse to respond to this emergency situation quickly.



Acetaminophen/Tylenol/Paracetamol acetylcysteine (Mucomyst)
Antcholinesterase atrophine sulfate or pralidoxime
Anticholinergics physostigmine
Benzodiazepines flumazenil
Beta blockers glucagon
Calcium channel blockers glucagon
Coumadin/Warfarin phytonadione (Vitamin K.)
Cyanide amyl nitrate, sodium nitrate, sodium thiosulfate
Cyclophosphamide mesna
Digoxin digibind
digoxine immune fab
Dopamine phentolamie (Regitine)
Extrapyramidal symptoms (EPS) diphenhydramine (Benadryl)
Ethylene glycol fomepizole
Fluorouracil leucoverin calcium
Heparin protamine sulfate
Insulin reaction glucose (Dextrose 50%)
Iron deferoxamine
Lead dimercapol, edetate calcium, disodium,
Methotrexate leucovorin calcium
Narcotics naloxone (Narcan)
Neuromuscular blockade (paralytics) anticholinesterase agents
Opioid analgesics nalmefene or naloxone
Potassium albuterol inhaler, insulin & glucose, NaHCO3, kayexalate
Tricyclic antidepressants phyostigmine or NaHCO3

Download this table: PDFWord Doc



  • Lakshitha Ishanka Galawalage

    Exellent job, thanks

  • Gerald Cordova Piñon

    Magnesium sulfate – calcium gluconate… to add in the list :)
    Would anyone post Drug of choice for specific disease or condition here. thanks :)

  • sarah

    can u please send me all natidote for all drugs thanks

  • nighat saeed

    a.a.can u please send me some guidelines for the establishment of poison contrl center in a hospital?