An antidote is a substance that can counteract a form of poisoning. The term antidote is a Greek word meaning “given against”.
This post will help you familiarize with the common antidotes that are used in the hospital setting.
The following are antidotes that should be familiarized by the nurse to respond to this emergency situation quickly.
Agent/Drug | Antidote |
| Acetaminophen/Tylenol/Paracetamol | acetylcysteine (Mucomyst) |
| Antcholinesterase | atrophine sulfate or pralidoxime |
| Anticholinergics | physostigmine |
| Benzodiazepines | flumazenil |
| Beta blockers | glucagon |
| Calcium channel blockers | glucagon |
| Coumadin/Warfarin | phytonadione (Vitamin K.) |
| Cyanide | amyl nitrate, sodium nitrate, sodium thiosulfate |
| Cyclophosphamide | mesna |
| Digoxin | digibind digoxine immune fab |
| Dopamine | phentolamie (Regitine) |
| Extrapyramidal symptoms (EPS) | diphenhydramine (Benadryl) |
| Ethylene glycol | fomepizole |
| Fluorouracil | leucoverin calcium |
| Heparin | protamine sulfate |
| Insulin reaction | glucose (Dextrose 50%) |
| Iron | deferoxamine |
| Lead | dimercapol, edetate calcium, disodium, |
| Methotrexate | leucovorin calcium |
| Narcotics | naloxone (Narcan) |
| Neuromuscular blockade (paralytics) | anticholinesterase agents |
| Opioid analgesics | nalmefene or naloxone |
| Potassium | albuterol inhaler, insulin & glucose, NaHCO3, kayexalate |
| Tricyclic antidepressants | phyostigmine or NaHCO3 |




