Nursing Pharmacology Practice Questions & Test Bank for NCLEX (500+ Questions)

Walter, a teenage patient is admitted to the hospital because of acetaminophen (Tylenol) overdose. Overdoses of acetaminophen can precipitate life-threatening abnormalities in which of the following organs?

A contraindication for topical corticosteroid usage in a male patient with atopic dermatitis (eczema) is:

In infants and children, the side effects of first-generation over-the-counter (OTC) antihistamines, such as diphenhydramine (Benadryl) and hydroxyzine (Atarax) include:

Reye’s syndrome, a potentially fatal illness associated with liver failure and encephalopathy is associated with the administration of which over-the-counter (OTC) medication?

The nurse is aware that the patients who are allergic to intravenous contrast media are usually also allergic to which of the following products?

A 13-month-old child recently arrived in the United States from a foreign country with his parents and needs childhood immunizations. His mother reports that he is allergic to eggs. Upon further questioning, you determine that the allergy to eggs is anaphylaxis. Which of the following vaccines should he not receive?

The cell and Coombs classification system categorizes allergic reactions and is useful in describing and classifying patient reactions to drugs. Type I reactions are immediate hypersensitivity reactions and are mediated by:

Drugs can cause adverse events in a patient. Bone marrow toxicity is one of the most frequent types of drug-induced toxicity. The most serious form of bone marrow toxicity is:

Serious adverse effects of oral contraceptives include:

The most serious adverse effect of Alprostadil (Prostin VR pediatric injection) administration in neonates is:

Mandy, a patient, calls the clinic today because he is taking atorvastatin (Lipitor) to treat his high cholesterol and is having pain in both of his legs. You instruct him to:

Which of the following adverse effects is associated with levothyroxine (Synthroid) therapy?

Which of the following adverse effects is specific to the biguanide diabetic drug metformin (Glucophage) therapy?

The most serious adverse effect of tricyclic antidepressant (TCA) overdose is:

The nurse is aware that the following solutions are routinely used to flush an IV device before and after the administration of blood to a patient is:

Chris asks the nurse whether all donor blood products are cross-matched with the recipient to prevent a transfusion reaction. Which of the following always require cross-matching?

A month after receiving a blood transfusion an immunocompromised male patient develops a fever, liver abnormalities, a rash, and diarrhea. The nurse would suspect this patient has:

Jonas comes into the local blood donation center. He says he is here to donate platelets only today. The nurse knows this process is called:

Nurse Bryan knows that the age group that uses the most units of blood and blood products is:

A child is admitted with a serious infection. After two days of antibiotics, he is severely neutropenic. The physician orders granulocyte transfusions for the next four days. The mother asks the nurse why? The nurse responds:

A neighbor tells nurse Maureen he has to have surgery and is reluctant to have any blood product transfusions because of a fear of contracting an infection. He asks the nurse what are his options. The nurse teaches the person that the safest blood product is:

A severely immunocompromised female patient requires a blood transfusion. To prevent GVHD, the physician will order:

Louie, who is to receive a blood transfusion asks the nurse what is the most common type of infection he could receive from the transfusion. The nurse teaches him that approximately 1 in 250,000 patients contract:

A male patient with blood type AB, Rh factor positive needs a blood transfusion. The Transfusion Service (blood bank) sends type O, Rh factor negative blood to the unit for the nurse to infuse into this patient. The nurse knows that:

Dr. Rodriguez orders 250 milliliters of packed red blood cells (RBC) for a patient. This therapy is administered for the treatment of:

A female patient needs a whole blood transfusion. In order for transfusion services (the blood bank) to prepare the correct product a sample of the patient’s blood must be obtained for:

A male patient needs to receive a unit of whole blood. What type of intravenous (IV) device should the nurse consider starting?

Dr. Smith orders a gram of human salt poor albumin product for a patient. The product is available in a 50-milliliter vial with a concentration of 25 percent. What dosage will the nurse administer?

Central venous access devices (CVADs) are frequently utilized to administer chemotherapy. What is a distinct advantage of using the CVAD for chemotherapeutic agent administration?

A female patient’s central venous access device (CVAD) becomes infected. Why would the physician order antibiotics be given through the line rather than through a peripheral IV line?

Chemotherapy dosing is usually based on the total body surface. What should the nurse do before administering chemotherapy?

The nurse is caring for a client who is receiving a chemotherapy. Which of the following would be expected as a result of the massive cell destruction that occurred from the chemotherapy?

Mitomycin (Mutamycin) is prescribed to a client with colorectal cancer. All of which are the routes of administration, except?

The client with a testicular cancer is being treated with Etoposide (Etopophos). Which of the following side effect is specifically associated with this medication?

The clinic nurse provides instructions to a client receiving an antineoplastic medication. When implementing the plan, the nurse tells the client to?

The client with non-Hodgkin’s lymphoma is being managed with vincristine (Vincasar). Which of the following indicates a side effect specific to this medication?

A client with sarcoma is receiving Bleomycin (Blenoxane). The nurse in charge of the client expects the physician to order which diagnostic procedure?

A male client with breast cancer is receiving Tamoxifen (Nolvadex). The nurse specifically monitors which laboratory value?

The client with ovarian cancer is receiving Tamoxifen (Nolvadex). Which of the following indicates a side effect specific to this medication?

The client with acute myelocytic leukemia is being treated with busulfan (Myleran). The nurse specifically monitors which laboratory value while the client is taking this medication?

The nurse is evaluating the medical history of a client who will be receiving Asparaginase (Elspar). The nurse contacts the health care provider if which of the following is noted in the history?

Megestrol acetate (Megace) is prescribed for a client with advanced breast cancer. The nurse reviews the client’s history and contacts the physician if which of the following is documented in the client’s history?

The client with non-Hodgkin’s lymphoma is receiving Idarubicin (Idamycin). Which of the following would indicate to the nurse that the client is experiencing an adverse effect related to the medication?

The client is receiving cisplatin (Platinol-AQ). Which of the following side effect is related to the medication?

The nurse is monitoring the laboratory results of a male client receiving antineoplastic medications. The nurse plans to initiate bleeding precautions if which laboratory is value is noted?

A client is receiving methotrexate (Rheumatrex) for a series of chemotherapy. Which of the following medication should be readily available to avoid toxicity?

The nurse is providing teachings to a client receiving cyclophosphamide (Cytoxan). The nurse tells the client to which of the following?

The nurse is monitoring a patient receiving an Iv infusion of an antineoplastic medication. During the infusion, the patient complains of pain and redness at the insertion site. The nurse should take which actions? Select all that apply.

The nurse is caring for a client receiving chemotherapy when an anaphylactic reaction occurs from the medication. The nurse should take which actions? Select all that apply.

The nurse is caring for a client who is receiving fluorouracil (Adrucil). Which of the following symptoms would necessitate the nurse to immediate discontinuation of the medication?