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Nursing Pharmacology Practice Questions & Test Bank for NCLEX (500+ Questions)
Updated on
By Matt Vera BSN, R.N.
Welcome to your ultimate set of nursing pharmacology questions for the NCLEX! In this nursing test bank, test your competence in nursing pharmacology with these 500+ practice NCLEX questions. This quiz aims to help nursing students review concepts of nursing pharmacology and provide an alternative to Quizlet or ATI.
Nursing Pharmacology Questions and Test Banks
In this section are the practice problems and questions for nursing pharmacology. There are 530+ nursing pharmacology practice questions in this nursing test bank partitioned into 11 parts. Nursing topics include medication administration, dosage calculations, general concepts about nursing pharmacology, cardiovascular drugs, antibiotics and anti-infectives, neurological medications, psychiatric medications, drugs for the respiratory system, gastrointestinal system, and endocrine system.
All questions on this set are updated to give you the most challenging questions, along with insightful rationales to reinforce learning.
Please be aware that our test banks are ALWAYS FREE OF CHARGE, and NO REGISTRATION IS REQUIRED. Nurseslabs HAVE NOT and WILL NEVER ASK for your credit card details or any personal information to access our practice questions. Nurseslabs is committed to making this service FREE AND ACCESSIBLE FOR ALL who wants to advance their careers especially students and nurses.
Quiz guidelines:
Comprehend each item. Read and understand each question before choosing the best answer. The exam has no time limit so that you can make sense of each item at your own pace.
Review your answers. Once you’re done with all the questions, you’ll be redirected to the Quiz Summary table, where you’ll be able to review which questions you’ve answered or may have skipped. Review your answers once more before pressing the Finish Quiz button.
Read the rationales. After you have reviewed your answers, click on the Finish Quiz button to record your answers and show your score. Click on the View Questions button to review the quiz and read through the rationales for each question.
Let us know your feedback! Comment us your thoughts, scores, ratings, and questions about the quiz in the comments section below.
Where are the rationales? Please click the View Questions button below to review your answers and read through the rationales for each question.
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Question 1 of 50
1. Question
A nurse provides instructions to a client taking fluoxetine (Prozac) a selective serotonin reuptake inhibitor (SSRI) antidepressant. The nurse tells the client to take the medication:
Correct
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Question 2 of 50
2. Question
The risk of experiencing serotonin syndrome when SSRIs are given with monoamine oxidase inhibitors such as phenelzine (Nardil). Serotonin syndrome is best characterized in which of the following?
Correct
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Question 3 of 50
3. Question
A client with depression who has been taking amitriptyline for three months returns to the clinic for a follow-up. The nurse observes the client in which of the following symptoms?
Correct
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Question 4 of 50
4. Question
A client is prescribed sertraline (Zoloft). To guarantee a safe administration of the medication, a nurse would administer the dose:
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Question 5 of 50
5. Question
A client arrives in the emergency room with a tricyclic antidepressant overdose. Which of the following measures should the nurse do, except?
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Question 6 of 50
6. Question
A newly admitted client has started taking bupropion (Wellbutrin). The nurse monitors which of the following side effects would indicate an overdosage of the medication?
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Question 7 of 50
7. Question
A nurse is giving discharge instructions to a client who is prescribed with isocarboxazid (Marplan). The nurse will tell the client to anticipate which of the following side effects of this medication?
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Question 8 of 50
8. Question
A client with depression is taking phenelzine (Nardil). The nurse advises the client to avoid consuming which foods while taking the medication
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Question 9 of 50
9. Question
Patients taking MAOIs have the tendency to experience hypertensive crisis especially during an interaction with other drugs such as epinephrine. Which of the following is a sign of hypertensive crisis?
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Question 10 of 50
10. Question
During a hypertensive crisis, the nurse makes sure which of this medicine is readily available?
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Question 11 of 50
11. Question
A client taking lithium carbonate (Lithobid) started complaining of nausea, vomiting, diarrhea, drowsiness, muscle weakness, tremor, blurred vision, and ringing in the ears. The lithium level is 2 mEq/L. The nurse interprets this value as:
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Question 12 of 50
12. Question
A nurse is giving instructions to a client receiving lithium citrate. The nurse tells the client to do which of the following to prevent lithium toxicity:
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Question 13 of 50
13. Question
Which of the following symptoms is classified as a mild lithium toxicity:
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Question 14 of 50
14. Question
A nurse is giving instructions to a client taking risperidone (Risperdal). The nurse advises the client to do which of the following?
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Question 15 of 50
15. Question
A nurse notes that a client with schizophrenia and receiving an antipsychotic medication is having uncontrolled movement of the lips and tongue. The nurse determines that the client is experiencing?
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Question 16 of 50
16. Question
A client with schizophrenia has been started on medication therapy with clozapine (Clozaril). A nurse assesses the results of which laboratory study to monitor for adverse effects related to this medication?
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Question 17 of 50
17. Question
Methylphenidate (Ritalin) is prescribed to an 8-year-old child for the treatment of attention deficit hyperactivity disorder (ADHD). The nurse will most likely monitor which of the following during the medication therapy?
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Question 18 of 50
18. Question
Which of the following medications that treat Alzheimer’s disease causes slowing of the heart rate and fainting episodes?
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Question 19 of 50
19. Question
A client who has been taking buspirone (BuSpar) for two months returns to the clinic for a follow-up. The nurse determines that the medication is effective if there is an absent display of?
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Question 20 of 50
20. Question
A nurse is giving discharge instructions to a client who will be taking phenobarbital (Luminal). The nurse would educate the client in which of the following directly correlates with the safety of the client?
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Question 21 of 50
21. Question
Which group of drugs mimics parasympathetic activity?
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Question 22 of 50
22. Question
Cholinergic agents are used to:
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Question 23 of 50
23. Question
Cholinergics are contraindicated in:
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Question 24 of 50
24. Question
Drugs that mimic sympathetic activity are known as: Drugs that mimic sympathetic activity are known as:
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Question 25 of 50
25. Question
Which of the following metabolic effects may be a consequence of the administration of adrenergic agents?
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Question 26 of 50
26. Question
Adrenergic blockers are contraindicated in:
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Question 27 of 50
27. Question
A side effect of cholinergic administration is:
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Question 28 of 50
28. Question
Joseph is a child diagnosed with attention deficit disorder. Which of the following drugs is commonly used for his condition?
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Question 29 of 50
29. Question
Amphetamines are included in the category of drugs of abuse because of their ability to:
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Question 30 of 50
30. Question
The nurse would monitor for decreased effect of amphetamines when these drugs are given with:
Correct
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Question 31 of 50
31. Question
As a knowledgeable nurse, you know that you should never give amphetamines in combination with:
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Question 32 of 50
32. Question
Use of methylphenidate for attention deficit disorders in children can result in:
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Question 33 of 50
33. Question
Amphetamines and amphetamine-like compounds are most commonly used for:
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Question 34 of 50
34. Question
When administering IV phenytoin (Dilantin), the nurse should:
Correct
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Question 35 of 50
35. Question
When caring for a client who is receiving phenytoin and warfarin (Coumadin), the nurse would expect which of the following drug-drug interactions?
Correct
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Question 36 of 50
36. Question
The client asks the nurse why he is taking bromocriptine (Parlodel). The nurse’s reply is based in the understanding that bromocriptine mimics the effects of dopamine by:
Correct
Incorrect
Question 37 of 50
37. Question
Before administering amantadine (Symadine), the nurse should investigate which of the following client statements?
Correct
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Question 38 of 50
38. Question
The priority nursing intervention for a client receiving amantadine is to teach the client to:
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Question 39 of 50
39. Question
Which of the following assessments is most essential before beginning a drug regimen of an antimuscarinic agent?
Correct
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Question 40 of 50
40. Question
The nurse evaluates that carbidopa and levodopa (Sinemet) is therapeutically effective if the client has:
Correct
Incorrect
Question 41 of 50
41. Question
For which of the following medical conditions would the nurse anticipate that an antianxiety agent would not be indicated?
Correct
Incorrect
Question 42 of 50
42. Question
When administering antianxiety medications to an elderly client, which of the following actions by the nurse is essential?
Correct
Incorrect
Question 43 of 50
43. Question
When monitoring a client who is taking benzodiazepines, the nurse should be alert for which CNS side effects?
Correct
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Question 44 of 50
44. Question
Antidepressants generally exert influence by:
Correct
Incorrect
Question 45 of 50
45. Question
The nurse performs an initial assessment and nursing history with a client admitted for a major depression. The client has a history of narrow-angle glaucoma. The nurse’s best action would be to:
Correct
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Question 46 of 50
46. Question
Antipsychotic drugs are indicated:
Correct
Incorrect
Question 47 of 50
47. Question
Sheila who has been on a low-potency antipsychotic for 2 weeks has shown minimal response. The most probable explanation is:
Correct
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Question 48 of 50
48. Question
Ansherina who is receiving a traditional antipsychotic agent complains that she is gaining weight. The nurse would:
Correct
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Question 49 of 50
49. Question
Drugs classified as centrally acting skeletal muscle relaxants are most effective in relieving:
Correct
Incorrect
Question 50 of 50
50. Question
Peripherally acting skeletal muscle relaxants are used:
Recommended books and resources for your NCLEX success:
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Nursing Pharmacology Review
Here are some study guides to help you review concepts about nursing pharmacology:
An investment in knowledge pays the best interest. Keep up the pace and continue learning with these practice quizzes:
Nursing Test Bank: Free Practice QuestionsUPDATED! Our most comprehenisve and updated nursing test bank that includes over 3,500 practice questions covering a wide range of nursing topics that are absolutely free!
NCLEX Questions Nursing Test Bank and ReviewUPDATED! Over 1,000+ comprehensive NCLEX practice questions covering different nursing topics. We’ve made a significant effort to provide you with the most challenging questions along with insightful rationales for each question to reinforce learning.
Matt Vera, a registered nurse since 2009, leverages his experiences as a former student struggling with complex nursing topics to help aspiring nurses as a full-time writer and editor for Nurseslabs, simplifying the learning process, breaking down complicated subjects, and finding innovative ways to assist students in reaching their full potential as future healthcare providers.
18 thoughts on “Nursing Pharmacology Practice Questions & Test Bank for NCLEX (500+ Questions)”
Thank you Vera for your wonderful work. You are really helpful to the world. God bless you
Thank you so much for your wonderful work Matt! I am preparing for NCLEX-PN exam, I was wondering this pharmacology quiz is related to RN or is it general for NCLEX?? Thanks
Thanks so much, Nurseslabs and staff. I passed the Prometric exam for Qatar!! Keep up the good work and share review questions for us, nurses. God bless and more power!
This site is amazing! Was searching for NCLEX study programs and came across this right before I was about to pay $200 for another program. Using this instead and saving so much money!
I think you have a TYPO in Respiratory Question 7 of 30
7. Question: Montelukast (Singulair) is prescribed to a client with asthma. During the medication therapy, which of the following laboratories should be monitored?
Your answer: Correct Answer: D. Alanine transaminase (ALT) and aspartate transaminase (AST)
Montelukast (Singulair) is a leukotriene receptor and is used with caution in clients with impaired renal function. Alanine aminotransferase (ALT) and Aspartate aminotransferase (AST) should be monitored while taking this medication.
ALT and AST are LIVER ENZYMES and singular should be used with caution with HEPATIC patients? Or am I mistaken? Why would you want to monitor liver enzymes for renal function? Wouldn’t you want to monitor creatinine and BUN instead for RENAL patients?
I think you need to change RENAL to HEPATIC but I could be wrong.
Thanks for having these questions though! Very helpful. 😊
Thank you Vera for your wonderful work. You are really helpful to the world. God bless you
Thanks very much. This’s very helpful
Thank you Vera. May god bless you for all.
God bless you Vera and all that made these possible and accessible. You are a great gift to humanity!
Bless you Joe, thanks for your kind words!
Thank you Matt! You are a blessing to us who are aspiring to be a RN.
This is very useful resources… Great job from everyone in the team, thank you…
I need a copy of this question in PDF form. Thanks
I need the full pdf of these questions
Which browser can l use to open above questions?
All modern browsers like Chrome, Safari, Firefox and Microsoft Edge.
Thank you so much for your wonderful work Matt! I am preparing for NCLEX-PN exam, I was wondering this pharmacology quiz is related to RN or is it general for NCLEX?? Thanks
This quiz has been helpful. Thank you very much
Thanks so much, Nurseslabs and staff. I passed the Prometric exam for Qatar!! Keep up the good work and share review questions for us, nurses. God bless and more power!
Congratulations Raymond! Good luck on your journey as a registered nurse! :) God bless!
Thank you so much. God bless you!
This site is amazing! Was searching for NCLEX study programs and came across this right before I was about to pay $200 for another program. Using this instead and saving so much money!
I think you have a TYPO in Respiratory Question 7 of 30
7. Question: Montelukast (Singulair) is prescribed to a client with asthma. During the medication therapy, which of the following laboratories should be monitored?
Your answer: Correct Answer: D. Alanine transaminase (ALT) and aspartate transaminase (AST)
Montelukast (Singulair) is a leukotriene receptor and is used with caution in clients with impaired renal function. Alanine aminotransferase (ALT) and Aspartate aminotransferase (AST) should be monitored while taking this medication.
ALT and AST are LIVER ENZYMES and singular should be used with caution with HEPATIC patients? Or am I mistaken? Why would you want to monitor liver enzymes for renal function? Wouldn’t you want to monitor creatinine and BUN instead for RENAL patients?
I think you need to change RENAL to HEPATIC but I could be wrong.
Thanks for having these questions though! Very helpful. 😊