Mebendazole Drug Study

Generic name: Mebendazole

Brand name: Vermox

Classifications: Antihelmintic

Therapeutic Actions

Irreversibly blocks glucose uptake by susceptible helminthes, depleting glycogen stores needed for survival and reproduction of helminths, causing death.

Indications

Treatment of Trichus trichiura (whipworm), Enterobius vermicularis (pinworm), Ascaris lumbricoides (roundworm), Ancylostoma duodenale (common hookworm), Necator anericanus (American hookworm).

Contraindications

Contraindicated with allergy to mebendazole, pregnancy (embryotoxic and teratogenic; avoid use, especially during first trimester). Use cautiously with lactation.

Adverse Effects

GI: transient abdominal pain, diarrhea
Other: fever
Chewable tablets- 100mg
Assess for pregnancy, lactation and allergy to mebendazole.
Assess for temperature, bowel sounds and output.
Culture for ova and parasites.
Ad mister drug with food; tablets may be chewed, swallowed whole, or crushed and missed with food.
Arrange for second course of treatment if patient is not cured 3weeks after treatment.
Treat all family members for pinworm infestation.
Disinfect toilet facilities after patient use. (pinworm)
Arrange for daily laundry of bed linens, towels, nightclothes, and undergarments. (pinworm)
Brown colored urine

Stock Dose

Chewable tablets- 100mg

Nursing Responsibilities

Assess for pregnancy, lactation and allergy to mebendazole.
Assess for temperature, bowel sounds and output.
Culture for ova and parasites.
Ad mister drug with food; tablets may be chewed, swallowed whole, or crushed and missed with food.
Arrange for second course of treatment if patient is not cured 3weeks after treatment.
Treat all family members for pinworm infestation.
Disinfect toilet facilities after patient use. (pinworm)
Arrange for daily laundry of bed linens, towels, nightclothes, and undergarments. (pinworm)
Give via side drip